Process Hygiene · CIP Units

CIP Units: Clean-in-Place Systems for Hygienic Production

Tanks, pipelines, heat exchangers and fillers cleaned where they stand, in the same proven sequence every time, with every temperature, flow and conductivity value on record.

Protrus CIP unit range: mobile CIP unit, compact three-tank CIP skid and four-tank CIP station with recovery

Protrus CIP units: from compact two-tank skids to four-tank CIP stations with recovery.

1.5–2.0 m/s

Minimum flow velocity in CIP pipelines

1.5–2.5 bar

Working pressure at tank spray balls

55–85 °C

Typical hot CIP temperature range

500 L – 10 m³

CIP tank sizes, mobile to central

What a CIP Unit Does

A CIP unit (clean-in-place unit) prepares, heats, pumps and recovers the cleaning solutions that clean a process plant from the inside, without opening a single clamp. It replaces manual cleaning with a closed, automated cycle of rinsing, alkaline and acid washing and sanitizing, run by recipe and confirmed by sensors.

Every food, beverage or pharmaceutical line leaves a film of fat, protein, sugar or minerals on its product-contact surfaces. If that film stays, it feeds bacteria, forms biofilm and carries taste, color or allergens into the next batch. A CIP unit removes it with four controlled forces: chemistry, temperature, flow and time.

Solutions are made up in dedicated tanks, pumped through the object at a velocity that creates turbulent flow, and routed back by conductivity so that strong chemicals return to their tanks and only clean water is reused. The result is the same cleaning result on every shift, lower water, energy and chemical use than manual cleaning, shorter downtime between batches and a cleaning record that supports HACCP, EC 853/2004, FDA 21 CFR 117 and GMP audits.

Protrus designs CIP units from a 500 L mobile skid for a single machine to central multi-tank stations that clean a whole dairy, in AISI 304/316L stainless steel, with hygienic valves, VFD-driven pumps, steam or electric heating and PLC/HMI control with full cycle records.

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Benefits of an Automated CIP Unit

Food safety.

No hidden soil or biofilm in pipes, valves and tank domes; fewer recalls and rejected batches.

Repeatable results.

The same recipe, flow and temperature on every shift, independent of the operator.

Less downtime.

Cleaning starts at the push of a button and runs while the next batch is prepared.

Lower costs.

Chemical and rinse water recovery cut water, energy, chemical and effluent costs.

Operator safety.

Closed handling of hot caustic and acid, no climbing into tanks.

Audit-ready.

Each cycle is logged with time, temperature, flow and conductivity for HACCP and GMP.

CIP Unit Configurations

From a 500 L mobile skid for a single machine to central multi-tank stations that clean a whole dairy: the configuration follows the plant, the number of circuits and how solutions are reused.

Mobile CIP unit

Tanks: 1–2 (e.g. 2 × 500 L)

Typical use

Single machines, pilot plants, sauce and caramel cookers, skids

Solution handling

Heated in tank, reused

Compact CIP skid

Tanks: 2–3 (alkali, acid, water)

Typical use

Small dairies, juice and beverage lines, one circuit at a time

Solution handling

Reuse of alkali and acid

Four-tank CIP unit with recovery

Tanks: 4 (alkali, acid, hot water, recovered water)

Typical use

Dairy, UHT and process plants with frequent CIP

Solution handling

Reuse + rinse water recovery

Multi-line central CIP station

Tanks: 4–6 + extra supply lines

Typical use

Large plants cleaning tanks and lines in parallel

Solution handling

Several circuits at once

Single-use CIP

Tanks: 1 make-up tank

Typical use

Pharma, biotech, high soil loads, allergen changeovers

Solution handling

Fresh solution each cycle

Satellite / decentral CIP

Tanks: Local tank + central chemicals

Typical use

Long distances, remote filling or reception areas

Solution handling

Short circuits, less volume

Ten steps

CIP Process: How a Clean-in-Place Cycle Works

Ten steps, each one ended by a measured value, not a stopwatch.

A CIP cycle starts before the first drop of chemical. Product left in the line is pushed out and recovered, loose soil is flushed by a pre-rinse, and only then does hot caustic remove fat and protein. An intermediate rinse keeps alkali and acid apart, the acid wash dissolves milkstone and scale, and the final rinse brings the line back to neutral.

Hot water or a disinfectant then lowers the microbial load before the plant is released. The Protrus PLC moves from step to step only when temperature, flow, return conductivity and time all meet the recipe.

A · Remove product and organic soil steps 1–5 · typical hot CIP values, final recipe set by validation

  1. 1Make-upWater + dosing + heatingConductivity check
  2. 2Product recoveryPush out with water, air or pigLess product loss
  3. 3Pre-rinseRecovered or fresh water3–10 min
  4. 4Alkaline washNaOH 0.5–2.0 %55–80 °C · 10–30 min
  5. 5Intermediate rinseUntil conductivity drops2–5 min

B · Remove minerals, rinse and release steps 6–10

  1. 6Acid washHNO₃ / H₃PO₄ 0.5–1.0 %50–70 °C · 10–20 min
  2. 7Final rinsePotable or RO water5–10 min · to set point
  3. 8SanitizationHot water or PAA80–90 °C or cold PAA
  4. 9VerificationATP, swab, pH, recordsBatch report
  5. 10Ready for productionDrained and releasedStart-up

Steps 3, 5 and 7 are switched by return conductivity, not only by time. Step 6 runs every cycle or at set intervals, depending on water hardness and mineral load.

Cold CIP (≤ 30 °C) keeps the same sequence with adapted chemistry, longer contact time and higher velocity; it suits clear juices, soft drinks and syrups.

Return routing

Strong solutionBack to its tank

Transition zoneRecovery tank or drain

Clean final rinseRecovery tank for the next pre-rinse

Temperature, Chemistry, Mechanics and Time

The four factors of Sinner’s circle work together: when one is lowered, another has to rise. Above 30 °C, each extra 10 °C makes the chemistry roughly 50 % more effective, but too much heat bakes protein onto the steel and ages gaskets.

Mechanical action comes from turbulence: pipelines need at least 1.5–2.0 m/s and a Reynolds number above 20,000, spray balls 1.5–2.5 bar. Valve clusters, tees, U-bends and dead legs are where velocity is lost first, so Protrus checks the hydraulics of the hardest circuit, not the average one.

Four factors of CIP performance

Sinner’s circle

Less of one factor must be balanced by more of the others.

Temperature and return conductivity during a CIP cycle

Illustrative profile · hot CIP with acid step

PRE-RINSEALKALINE WASHINTERM. RINSEACID WASHFINAL RINSEHOT WATER 020 °C40 °C60 °C80 °C NaOH ≈ 1.5 %→ high conductivityacid ≈ 0.8 % time → (typical total 60–90 min)
Supply temperatureReturn conductivity, relative (switches valves between steps)

Left: the four cleaning factors. Right: supply temperature and return conductivity over one hot CIP cycle; conductivity shows exactly when caustic, acid and water arrive back at the unit.

Choosing the Cleaning Chemistry

SoilWhere it formsTypical approachHow it works
Fat, oil, cream filmMilk, cream, sauces, cosmetic emulsionsHot alkali + surfactantSaponifies and emulsifies fat
Protein, burnt-on layerPasteurizers, UHT, evaporators, yogurtNaOH 1–2 %, enzyme or oxidizer if neededSwells and dissolves protein
Sugar, starch, caramelSyrups, juice, confectionery, saucesHot pre-rinse, then mild alkali or amylaseDissolves and hydrolyzes
Pectin, pulp, colloidsPulpy juice, tomato, fruit preparationsAlkali + pectinase, periodic acidBreaks gel structures
Milkstone, scale, mineralsHeated dairy surfaces, hard waterHNO₃ or H₃PO₄ 0.5–1.0 %Dissolves Ca and Mg salts
Biofilm, microbesFermenters, fillers, cold linesPAA, peroxide or hot water 80–90 °COxidizes and inactivates

Hot, Cold and Hybrid CIP

The temperature strategy follows the soil: heated, high-protein and high-fat products need hot CIP, clear low-soil lines can save heating energy with cold CIP.

Hot CIP

Alkali 55–80 °C · acid 50–70 °C · 60–90 min

The safe choice for milk, cream, UHT/ESL, high-protein, high-fat and starchy products and any heated surface.

Cold CIP

≤ 30 °C · 1.8–2.0 m/s or more

Adapted chemistry and longer contact time. It cuts heating energy for clear juices, soft drinks, syrups and other low-soil lines.

Hybrid CIP

Cold routine · hot at intervals

Cold CIP for routine cycles, hot CIP at defined intervals or when ATP, swab or heat transfer data ask for it.

Recovery

Caustic, acid and rinse water

Caustic and acid return to their tanks while concentration is right; the clean end of the final rinse becomes the next pre-rinse, saving water and effluent load.

Four-tank CIP unit with valve station and alkali, acid, hot water and recovered water tanks

Four-tank CIP unit with valve station: alkali, acid, hot water and recovered water tanks.

CIP Unit Design: Tanks, Pumps, Heating and Automation

A CIP unit is sized for the hardest circuit in the plant, not for the biggest tank.

Before any tank is drawn, Protrus engineers list every object to be cleaned: tanks and their spray devices, pipelines with their length and diameter, heat exchangers, fillers and membranes.

From that list come the number of circuits that must run at the same time, the flow and pressure of the most demanding route, the solution volume that route needs and the heating duty. Tank count, tank volume, pump, heat exchanger and automation level follow from these numbers.

Four-tank CIP unit with recovery · basic layout one supply line · one return line · PLC recipe control

ALKALIACIDHOT WATERRECOVERED NaOH 1–2 %HNO₃ 0.5–1 %80–90 °Crinse water LTLTLTLTFTTTQT Chemical dosingSupply pumpHeat exchangerProcess tankReturn pumpCIP RETURNCIP SUPPLY NaOH · acid · PAAVFD controlledsteam or hot waterspray ball 1.5–2.5 bar+ pipelines, valves, HXlow-level switchflow · temp.conductivitydrain steam 3 bar(g)

Basic layout of a four-tank CIP unit with recovery: one supply line, one return line, divert valves switched by return conductivity.

Four-tank CIP skid with tubular heat exchanger, flowmeter and CIP supply and return pumps
CIP valve manifold with pneumatic actuators, supply pumps and service platform

Four-tank CIP skid with tubular heat exchanger, flowmeter and CIP pumps; inset: valve manifold with supply pumps.

Main Components of a Protrus CIP Unit

Tanks. Insulated 316L tanks for alkali and acid, 304 or 316L tanks for water and recovered water; cone bottom, 360° spray ball, hygienic vent with overflow pan, Ø500 mm manhole.

Level control. High and low level switches plus a level transmitter; the low-level switch protects the pump from dry running.

Pumps. Centrifugal CIP supply pump with VFD and electromagnetic flowmeter; self-priming or centrifugal return pump.

Heating. Tubular or plate heat exchanger with steam or hot water (or electric heating on mobile units), 65–85 °C control.

Sensors. Inductive conductivity, temperature and pressure transmitters on supply and return.

Valves and automation. Hygienic mix-proof and butterfly valves, automatic chemical dosing, PLC with HMI, remote access and cycle logging.

Sizing the CIP Pump and Tanks

Flow is set by velocity in the pipe or by the spray device, whichever needs more; head adds up the losses on the way.

PipeFlow at 1.5 m/sLoss
DN25 (1″)2.9 m³/h0.010 bar/m
DN32 (1¼”)4.4 m³/h0.008 bar/m
DN40 (1½”)6.2 m³/h0.007 bar/m
DN50 (2″)10.6 m³/h0.005 bar/m
DN65 (2½”)18.5 m³/h0.004 bar/m
DN80 (3″)27.9 m³/h0.003 bar/m
DN100 (4″)42.5 m³/h0.002 bar/m

Practical CIP flow per pipe size at 1.5 m/s and approximate pressure loss.

Pump flow. The larger of the pipeline need (velocity) and the spray device need sets the flow.

Pump head. Spray device pressure plus line losses in supply and return, with fittings.

Tank volume. Twice the volume of the longest line, plus a 1.5 mm film on the cleaned surfaces, plus 60 seconds of pump flow for the return delay, times a safety factor of 1.3–1.5.

Circuits. One supply pump cleans one object at a time. Parallel cleaning needs its own supply line and pump for each circuit, never an uncontrolled split of one flow.

Worked example

Flow

10.6 m³/h

A 10 m³ tank whose spray ball needs 10 m³/h at 2.0 bar, fed by a DN50 line (10.6 m³/h at 1.5 m/s).

Head

2.6 bar

100 m of DN50 supply and return with fittings adds about 0.6 bar to the 2.0 bar at the spray ball.

Duty point

12 m³/h · 2.8 bar

With a 1.1 margin on flow and head, the CIP supply pump is selected for this point.

Built for Hygiene and Service Access

Every Protrus CIP unit is built to drain fully, to be reached safely and to keep a record of each cycle.

Four-tank stainless steel CIP skid with service platform, stairs and control cabinet

Skid with service platform and stairs

Four-tank CIP skid with return header and divert valves, viewed from above

Return header with divert valves

Central CIP station with steam heating, plate heat exchanger, supply pump and hygienic valves

Central station with steam heating

Four-tank CIP skid front view with stainless control cabinet, access stairs and cone-bottom tanks

Front view: stainless control cabinet and access stairs

Top view of a four-tank CIP skid with spray ball connections, pipework and guard rails

Top view: spray ball connections, pipework and guard rails

Tanks

Welded by robotic pulsed TIG to EN ISO 5817.

Pipework

EN 10357 and DIN 11851/11852, sloped for full drainage.

Utilities

For a 10 m³/h three-tank unit: steam 3 bar(g) at about 250 kg/h, RO or potable water 2 bar(g), air 6–7 bar(g).

HMI and data

Stores recipes, trends and alarms and exports every cycle to Excel or the plant MES.

CIP Applications: Dairy, Food & Beverage, Biotech, Personal Care and Pharma

The same engineering principles, tuned to the soil, the product risk and the documentation each industry needs.

Dairy and food and beverage plants are where most CIP units work, and where cleaning frequency, energy and water use matter most. Biotechnology, personal care and pharmaceutical producers add stricter demands: higher water quality, residue limits, validated recipes and traceable records.

Protrus adapts tank materials, chemistry, rinse water quality and automation to each case. For a complete dairy, see our process technology for dairy.

Dairy products cleaned with CIP: milk, yogurt and cheese

Dairy

Equipment cleaned
Milk reception, pasteurizers, UHT, separators, yogurt and cheese tanks, fillers

Main soils and risks
Protein and fat film, milkstone, spore formers

CIP focus
Hot alkali every cycle, acid daily or by run time, recovery

Beverage products cleaned with CIP: juice, sparkling drink and soft drink

Beverages

Equipment cleaned
Juice and syrup lines, soft drink mixing, brewing

Main soils and risks
Sugar, pectin, pulp, flavor and color carry-over

CIP focus
Product recovery, hot pre-rinse, cold or hybrid CIP where possible

Food and sauce products cleaned with CIP: caramel sauce, ketchup and ready meals

Food, sauces

Equipment cleaned
Sauces and ready meals

Main soils and risks
Sugar, pectin, pulp, flavor and color carry-over

CIP focus
Product recovery, hot pre-rinse, cold or hybrid CIP where possible

Biotechnology: stainless steel bioreactor and culture flask

Biotechnology

Equipment cleaned
Fermenters, media and harvest tanks, centrifuges, membranes

Main soils and risks
Cells, proteins, antifoam, biofilm

CIP focus
Validated recipes, TOC and conductivity checks, CIP followed by SIP

Personal care products: lotion, face cream and shampoo

Personal care

Equipment cleaned
Emulsion and gel mixers, storage tanks, filling machines

Main soils and risks
Oils, waxes, polymers, fragrance and color

CIP focus
Surfactant alkali, longer contact, changeover verification

Pharmaceutical liquids: oral syrup, vials and ampoules

Pharmaceutical

Equipment cleaned
Process vessels, transfer lines, syrup and liquid lines

Main soils and risks
Active ingredients, excipients, allergens

CIP focus
Single-use CIP, purified water or WFI final rinse, GMP records

Process tank farm with valve matrix and service platform, cleaned by a central CIP station
Process tank farm with CIP supply and return pipelines, mix-proof valves and pumps

Process tank farm with valve matrix, cleaned by a central CIP station; inset: CIP supply and return lines.

CIP as Part of the Whole Plant

In a complete plant the CIP station is linked to every tank and line through valve matrices, swing bends or flow plates. Mix-proof valves keep product and cleaning solution safely apart, so one tank can be cleaned while its neighbor is filling.

Protrus plans CIP circuits together with the process, so each tank, line and heat exchanger has a defined route, a known flow and a recipe of its own. On a UHT unit, CIP runs by run time and heat transfer data.

Mobile CIP unit with two heated 500 L tanks, CIP pump and stainless control panel on castors

Mobile CIP unit with two heated tanks, pump and control panel on castors.

Mobile CIP Units

One compact CIP unit on castors for single machines, pilot plants and new lines, ready before the central CIP is installed.

2 × 500 L

insulated 316L tanks

3 × 7.5 kW

electric heating per tank

4 kW

centrifugal CIP pump

  • Two 500 L insulated 316L tanks, built-in electric heating (3 × 7.5 kW per tank) with temperature hold during the caustic step
  • 4 kW centrifugal CIP pump, rotary spray devices, high/low level switches, temperature transmitter, optional inductive conductivity
  • AISI 304 skid on castors with a stainless control panel: temperature controller or PLC with HMI
  • Moves between machines: sauce and caramel cookers, small pasteurizers, mixers, pilot plants and new lines before the central CIP is ready

Cleaning Validation and Records

Validation proves that a recipe reaches the required hygiene level; routine verification shows that it still does. Protrus units record temperature, flow, conductivity and time for every step.

Supported checks

  • Temperature, flow, conductivity and time logged for every step
  • ATP swabs
  • Microbiological samples
  • Final rinse conductivity and pH
  • Riboflavin coverage tests for spray devices
  • TOC or product-specific residue analysis in pharma and biotech

Frequently Asked Questions About CIP Units

Have a question about your CIP circuits, chemistry or sizing? Ask our process engineers.

A CIP unit (clean-in-place unit) prepares, heats, pumps and recovers the cleaning solutions that clean tanks, pipelines, heat exchangers and fillers from the inside, without dismantling them. It runs rinsing, alkaline and acid washing and sanitizing as an automated recipe, confirmed by temperature, flow and conductivity sensors.

A typical hot CIP cycle runs product recovery, pre-rinse, alkaline wash, intermediate rinse, acid wash, final rinse and sanitization, followed by verification and release. The PLC moves to the next step only when temperature, flow, return conductivity and time meet the recipe. A typical total is 60–90 minutes. See the ten CIP steps above.

Typical values are NaOH 0.5–2.0 % at 55–80 °C (131–176 °F) for 10–30 minutes and nitric or phosphoric acid 0.5–1.0 % at 50–70 °C (122–158 °F) for 10–20 minutes. Sanitization uses hot water at 80–90 °C (176–194 °F) or cold PAA. The final recipe is set by validation.

CIP pipelines need at least 1.5–2.0 m/s (4.9–6.6 ft/s) and a Reynolds number above 20,000 for turbulent flow. Tank spray balls work at 1.5–2.5 bar (22–36 psi). Protrus checks the hydraulics of the hardest circuit, because valve clusters, tees and dead legs lose velocity first.

Hot CIP runs alkali at 55–80 °C and acid at 50–70 °C and suits milk, cream, UHT/ESL, high-protein, high-fat and starchy products. Cold CIP runs at 30 °C (86 °F) or below with adapted chemistry, longer contact time and 1.8–2.0 m/s or more; it cuts heating energy for clear juices, soft drinks and syrups. Hybrid CIP combines both.

Usually at the end of each production day or after a set run time; UHT and evaporators by run time and heat transfer data. Acid frequency depends on water hardness and mineral load.

Yes, one circuit at a time per supply pump. For parallel cleaning, Protrus adds supply lines and pumps so each circuit keeps its own flow, temperature and concentration.

For the hardest circuit in the plant, not the biggest tank. Pump flow is the larger of the pipeline and spray device need, pump head adds spray pressure and line losses, and tank volume is twice the longest line volume plus surface film and 60 seconds of return delay, times 1.3–1.5. In the example above, the duty point is 12 m³/h (about 53 US gpm) at 2.8 bar (41 psi).

A mobile CIP unit cleans single machines such as sauce and caramel cookers, small pasteurizers, mixers and pilot plants, and new lines before the central CIP is ready. The Protrus version has two 500 L (132 gal) insulated 316L tanks with electric heating, a 4 kW CIP pump and a control panel on castors.

Conductivity shows exactly when caustic, acid and water arrive back at the unit. Divert valves send strong solution back to its tank, the transition zone to the recovery tank or drain and clean final rinse to the recovery tank for the next pre-rinse, which saves chemicals, water and effluent.

Validation proves that a recipe reaches the required hygiene level; routine verification shows that it still does. Protrus units log every step and support ATP swabs, microbiological samples, final rinse conductivity and pH, riboflavin coverage tests and, in pharma and biotech, TOC or residue analysis. Ask our engineers about your validation plan.

Get a Quote

Plan Your CIP Unit with Protrus

Send us your plant layout or a list of the tanks, lines and heat exchangers to be cleaned, the longest CIP route, the products you run and how many circuits must be cleaned at the same time. Our engineers return the CIP circuit plan, tank and pump sizing, a P&ID, a 3D layout and a budget offer, for a mobile unit, a compact skid or a central multi-line CIP station.

  • Plant layout or list of tanks, lines and heat exchangers
  • Length and diameter of the longest CIP route
  • Products you run and their soils
  • Circuits to be cleaned at the same time

Prefer email? info@protrus.com

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