Process Technology · Homogenization

High Pressure Homogenizers for Dairy, Food, Chemical, Cosmetic and Pharma Production

Finer droplets, uniform particles and products that stay stable on the shelf, from a 25 L/h laboratory unit to a 30,000 L/h dairy line.

Protrus N-G10 high pressure homogenizer with two-stage valve and touch-panel control

N-G10 high pressure homogenizer: up to 10,000 L/h at 200 bar, two-stage valve, touch-panel control.

200–1,500 bar

Homogenizing pressure range

20–30,000 L/h

Capacity, laboratory to dairy line

2.2–250 kW

Installed main motor power

0.2–1 µm

Typical droplet size after homogenizing

What Is High Pressure Homogenization?

Pressure turned into velocity, and velocity into smaller droplets and particles.

A high pressure homogenizer pumps a liquid to between 200 and 1,500 bar and forces it through a gap a fraction of a millimeter wide. In that gap, fat globules, oil droplets, solid particles and even living cells are broken down to a uniform size, often below one micron.

Many liquids are mixtures of phases that do not want to stay together: fat in milk, oil in mayonnaise or cream, pigment in paint, soap fibers in grease, cells in a fermentation broth. Left alone, they cream, settle, separate or feel grainy.

Homogenization turns pressure into velocity: a plunger pump raises the product to high pressure, and the homogenizing valve releases it through a narrow gap at 100–300 m/s. Turbulence, cavitation and shear break droplets and particles apart, and the much larger surface is covered by proteins or emulsifiers, which keeps the product stable. The result is a uniform product with a longer shelf life, better mouthfeel or texture, brighter color and less need for additives.

Protrus offers twelve homogenizer models in three families: large and mid-size G-series machines for high-volume lines, compact HM-series machines for flexible production, and pilot and laboratory units for R&D, scale-up and high-pressure work in biotech and pharma.

Dairy products processed with a high pressure homogenizer
Dairy
Food and beverage products processed with a high pressure homogenizer
Food & beverage
Chemical and petrochemical products processed with a high pressure homogenizer
Chemical & petrochemical
Biotechnology products processed with a high pressure homogenizer
Biotechnology
Personal care products processed with a high pressure homogenizer
Personal care
Pharmaceutical products processed with a high pressure homogenizer
Pharmaceutical

The Protrus Homogenizer Range at a Glance

Four families from laboratory to central dairy. Every model is listed with its three rated pressure points in the model overview.

FamilyModelsCapacityMax. pressureTypical use
Large industrial (G-series)T-G30, E-G20, V-G157,500–30,000 L/h400 barCentral dairies, UHT and ESL lines, juice and beverage plants
Mid-size industrial (G-series)N-G10, N-G54,000–10,000 L/h400 barMilk, ice cream mix, cream, sauces, plant-based drinks
Compact industrial (HM-series)N-HM100, A-HM60, M-HM30, F-HM20750–10,000 L/h400 barMid-size plants, cosmetics, grease, paints and chemicals
Pilot and laboratoryS-HM5, C-HM125–500 L/h1,500 barR&D, scale-up, cell disruption, nano-emulsions, liposomes

Why Homogenize?

No separation

No cream line in milk, no oil ring in sauces, no sediment in juices and drinks.

Longer shelf life

Stable emulsions and suspensions survive storage, transport and temperature changes.

Better texture

Creamier mouthfeel, smoother creams and lotions, glossy and uniform grease.

Fewer additives

Fine droplets need less emulsifier, stabilizer or thickener for the same result.

Higher yield

More viscosity or consistency from the same recipe, for example firmer grease with less soap.

Better uptake

Smaller particles and droplets improve digestibility and bioavailability of actives.

High Pressure Homogenizer Models: From 25 L/h to 30,000 L/h

Twelve models, each rated at three pressure points, so the capacity you need is always matched to the pressure your product needs.

Every homogenizer delivers a fixed volume per stroke, so its capacity depends on the pressure it has to reach: the higher the pressure, the lower the flow for the same motor. The cards below show each model at three typical pressure points.

Industrial models are built for continuous duty up to 400 bar; pilot and laboratory models reach 1,500 bar for cell disruption, nano-emulsions and scale-up trials.

Industrial High Pressure Homogenizers

Protrus homogenizer T-G30 model
Homogenizer T-G30
  • 30,000 L/h at 200 bar
  • 25,000 L/h at 300 bar
  • 20,000 L/h at 400 bar
Protrus homogenizer E-G20 model
Homogenizer E-G20
  • 20,000 L/h at 200 bar
  • 15,000 L/h at 300 bar
  • 10,000 L/h at 400 bar
Protrus homogenizer V-G15 model
Homogenizer V-G15
  • 15,000 L/h at 200 bar
  • 10,000 L/h at 300 bar
  • 7,500 L/h at 400 bar
Protrus N-G10 high pressure homogenizer with two-stage valve and touch-panel control
Homogenizer N-G10
  • 10,000 L/h at 200 bar
  • 7,500 L/h at 250 bar
  • 5,000 L/h at 400 bar
Protrus homogenizer N-G5 model
Homogenizer N-G5
  • 7,500 L/h at 200 bar
  • 5,000 L/h at 300 bar
  • 4,000 L/h at 400 bar
Protrus homogenizer N-HM100 model
Homogenizer N-HM100
  • 10,000 L/h at 200 bar
  • 7,500 L/h at 250 bar
  • 5,000 L/h at 400 bar
Protrus homogenizer A-HM60 model
Homogenizer A-HM60
  • 5,000 L/h at 200 bar
  • 3,000 L/h at 300 bar
  • 2,500 L/h at 400 bar
Protrus homogenizer M-HM30 model
Homogenizer M-HM30
  • 3,000 L/h at 200 bar
  • 2,000 L/h at 300 bar
  • 1,000 L/h at 400 bar
Protrus homogenizer F-HM20 model
Homogenizer F-HM20
  • 2,000 L/h at 200 bar
  • 1,500 L/h at 300 bar
  • 750 L/h at 400 bar

Pilot Plant and Laboratory Homogenizers

Protrus homogenizer S-HM5 ultra-high-pressure version on a frame with feed tank
Homogenizer S-HM5ultra-high-pressure version
  • 250 L/h at 500 bar
  • 125 L/h at 1,000 bar
  • 50 L/h at 1,500 bar
Protrus homogenizer S-HM5 high-flow pilot version
Homogenizer S-HM5high-flow pilot version
  • 500 L/h at 200 bar
  • 200 L/h at 500 bar
  • 100 L/h at 1,000 bar
Protrus homogenizer C-HM1 laboratory unit on mobile frame
Homogenizer C-HM1laboratory unit on mobile frame
  • 60 L/h at 400 bar
  • 40 L/h at 600 bar
  • 25 L/h at 1,000 bar

How to Choose the Right Model

Six questions decide the model, the valve and the build. Our engineers check them against your product data or a pilot trial.

1. Pressure. Set by the product and the target droplet or particle size (see the pressure guide below).

2. Capacity. The flow your line needs at that pressure; pick the model whose rated point covers it with a margin.

3. Power. Approximate shaft power: kW = flow (m³/h) × pressure (bar) ÷ 36 ÷ 0.85. Example: 10 m³/h at 200 bar needs about 65 kW.

4. Stages. Two-stage valves for dairy, creams and most emulsions; single stage for some suspensions and cell disruption.

5. Materials. Stainless steel for food; hardened, ceramic or tungsten carbide valves for abrasive and high-solids products.

6. Hygiene. CIP and SIP ready product path, aseptic design with sterile plunger flushing when the homogenizer runs after UHT.

Standard Equipment and Options

AreaStandardOptions
PumpThree plungers, monoblock pump head, sanitary suction and discharge valvesFive plungers for very large flows, duplex or super duplex blocks
Homogenizing valveTwo-stage valve with hydraulic or pneumatic pressure settingCeramic or tungsten carbide seats and forcers, special valve geometries
DriveMain motor with V-belt or gearbox, oil-bath crankcase with coolingFrequency converter for variable flow, low-noise enclosure
ControlTouch panel, pressure transmitters, safety valve, low-oil and overpressure alarmsPLC integration with the line, remote access, batch records
HygieneCIP-ready product path, polished product-contact surfacesAseptic execution with sterile barrier, SIP, 3-A or EHEDG-oriented design

How it works

Homogenization Process: How a High Pressure Homogenizer Works

A plunger pump builds the pressure, a precision valve turns it into energy where it is needed: in a gap thinner than a hair.

Every high pressure homogenizer has two working parts. The plunger pump draws in product from a feed pump and pushes it, stroke by stroke, to the set pressure; its capacity is fixed by plunger diameter, stroke and speed.

The homogenizing valve then creates the resistance that holds that pressure and releases the product through a gap of 15–300 µm. Almost all the pressure energy is converted into turbulence, cavitation and shear in that gap, and a small part into heat: roughly 2–2.5 °C per 100 bar.

Working principle of a high pressure homogenizer: balance tank, feed pump, plunger pump block and two-stage homogenizing valve

Working principle: balance tank, feed pump, main motor and crankcase, plunger pump block and two-stage homogenizing valve. One of three (or five) plungers shown; typical values.

Homogenizing valve diagram: acceleration, turbulence, cavitation and shear in the gap reduce droplets from 2-10 µm to 0.2-1 µm

Homogenizing valve: the gap, the impact ring and droplet size before and after.

Single-Stage and Two-Stage Homogenization

First stage. Takes the full pressure drop and does the actual size reduction. Pressure is chosen by the product: 150–250 bar for milk, up to 1,500 bar for nano-emulsions.

Second stage. Adds a back-pressure of 10–20 % of the first stage. It breaks up clusters of freshly covered fat globules, keeps viscosity under control and makes cavitation in the first stage more stable.

Temperature. Fat must be liquid: dairy is homogenized at 55–80 °C, grease at 80–120 °C. Cold product means coarse droplets and more wear.

Passes. Cell disruption and nano-emulsions often need two to five passes at high pressure to reach full yield or a narrow size range.

Typical Homogenizing Pressure by Application

First-stage pressure in bar, confirmed by trials. Industrial models T-G30 to F-HM20 reach up to 400 bar; pilot and laboratory models S-HM5 and C-HM1 up to 1,500 bar.

Chart of typical homogenizing pressure by application, from 50 bar for cream to 1,500 bar for cell disruption and liposomes

Where the Homogenizer Sits in the Line

Pasteurization lines. After the regenerative section at 55–70 °C, before final heating, so the product is homogenized warm and then pasteurized.

UHT, upstream. Before the UHT heater: simple, non-aseptic design, the standard choice for most milk drinks.

UHT, downstream. After UHT heating, as an aseptic homogenizer: best texture and stability for cream, coffee creamers and high-protein drinks.

Partial homogenization. Only the cream stream is homogenized and remixed with skim milk: a smaller machine and much lower energy use.

See how the homogenizer fits a complete line in our UHT plants and process technology for dairy.

Applications

Homogenizer Applications: Dairy, Food & Beverage, Chemical and Petrochemical

One principle, many products: pressure, valve, materials and hygiene level change with what you make.

The homogenizer is the step that decides whether a product stays uniform. In food and dairy it prevents creaming, settling and grainy texture; in chemical plants it turns pastes and emulsions into smooth, stable products. These are the products our customers homogenize most often.

Dairy

Milk, UHT and ESL milk, cream and coffee creamers, yogurt and ayran, butter and buttermilk, ice cream mix, cream cheese, infant formula and baby food, puddings and desserts. 150–250 bar at 55–80 °C with a two-stage valve stops creaming, gives yogurt a firmer body, ice cream a smoother and drier texture and infant formula a stable emulsion.

UHT and ESL milk homogenized with a high pressure homogenizer
UHT and ESL milk
Cream homogenized with a high pressure homogenizer
Cream
Yogurt and ayran homogenized with a high pressure homogenizer
Yogurt, ayran
Butter homogenized with a high pressure homogenizer
Butter
Ice cream homogenized with a high pressure homogenizer
Ice cream
Cream cheese homogenized with a high pressure homogenizer
Cream cheese
Baby food homogenized with a high pressure homogenizer
Baby food
Puddings homogenized with a high pressure homogenizer
Puddings

Food & Beverage

Fruit juices and nectars keep their cloud; ketchup and tomato products gain viscosity from the same solids; mayonnaise and dressings stay stable with less egg yolk; honey and molasses become smooth and pourable without crystal lumps; soy, oat and nut drinks lose their chalky feel at 200–600 bar; jellies and fruit preparations get an even texture.

Fruit juice homogenized with a high pressure homogenizer
Fruit juice
Ketchup and sauces homogenized with a high pressure homogenizer
Ketchup, sauces
Mayonnaise and dressings homogenized with a high pressure homogenizer
Mayonnaise, dressings
Honey homogenized with a high pressure homogenizer
Honey
Molasses homogenized with a high pressure homogenizer
Molasses
Soy and plant drinks homogenized with a high pressure homogenizer
Soy, plant drinks
Jelly homogenized with a high pressure homogenizer
Jelly

Chemical & Petrochemical

Lubricating grease, lubricating oils and additive packages, paints and coatings, detergents, wax emulsions, resins and polymer dispersions, and water-in-fuel emulsions. Here the homogenizer works with viscous, sometimes abrasive products, so the design adds a positive feed pump, hardened or tungsten carbide valve parts and heated or insulated product paths.

Lubricating grease homogenized with a high pressure homogenizer
Lubricating grease
Grease cartridges homogenized with a high pressure homogenizer
Grease cartridges
Lubricating oil homogenized with a high pressure homogenizer
Lubricating oil
Paints and emulsions homogenized with a high pressure homogenizer
Paints, emulsions
Detergents homogenized with a high pressure homogenizer
Detergents
Wax homogenized with a high pressure homogenizer
Wax
Resins homogenized with a high pressure homogenizer
Resins
Fuel homogenized with a high pressure homogenizer
Fuel

Homogenizers in Grease Production

Typical lithium / lithium-complex soap grease: where the homogenizer works in the line.

Lubricating grease · where the homogenizer works typical lithium / lithium-complex soap grease

  1. 1Raw materialsBase oil, fatty acid, LiOHWeighed batch
  2. 2ReactorSaponification180–210 °C
  3. 3Finishing kettleCooling, cut-back oil, additives80–120 °C
  4. 4Feed pumpGear or lobe pump3–6 bar inlet
  5. 5HomogenizerMilling of soap fibers150–400 bar
  6. 6DeaeratorRemoves entrained airVacuum
  7. 7Filter + fillCartridges, tubs, drumsNLGI checked

Result

Smooth, glossy grease · higher yield (firmer NLGI grade with less soap) · less oil bleed · stable consistency batch after batch

Why. After saponification and cooling, soap fibers form bundles and lumps. Milling them through a homogenizing valve gives smooth, glossy grease with a uniform structure.

Yield. Finer, better dispersed fibers build more consistency: the target NLGI grade is reached with less thickener, which lowers raw material cost.

Quality. Less oil bleed, better mechanical and shear stability and the same penetration value batch after batch.

Settings. Typically 150–400 bar at 80–120 °C, one or two passes; a gear or lobe pump feeds the homogenizer and a deaerator removes the air before filling.

Typical Settings by Application: Dairy, Food and Chemicals

ApplicationPressureStages and temperatureDesign notes
Milk, cream, ice cream mix, yogurt100–250 barTwo stage, 55–80 °CSanitary design, CIP; aseptic after UHT
Juices, ketchup, tomato products100–300 barOne or two stage, 60–75 °CPulp and fiber tolerant valves
Soy, oat and nut drinks200–600 barTwo stage, 70–85 °C, 1–2 passesOften combined with UHT
Lubricating grease150–400 barSingle stage, 80–120 °CPositive feed pump, hardened valve, heated lines
Paints, wax and resin emulsions200–500 barOne or two stageWear-resistant valve parts, solvent-proof seals

Homogenizer Applications: Biotechnology, Personal Care and Pharmaceutical

Higher pressures, smaller batches and stricter hygiene: where pilot and laboratory homogenizers do their best work.

In life science and cosmetics the homogenizer often works at 600–1,500 bar, in several passes and with sterile or aseptic design. The pilot and laboratory models S-HM5 and C-HM1 cover this range and give results that scale up directly to the industrial models.

Biotechnology

Cell disruption releases intracellular products from bacteria such as E. coli, from yeast, algae and other cells: recombinant proteins and enzymes, insulin precursors, viral vectors and virus-like particles for vaccines, pigments and oils. Typical: 600–1,500 bar, one to five passes, product cooled to 4–10 °C between passes. See also our yeast cell disruption system.

Bacteria homogenized with a high pressure homogenizer
Bacteria
Yeast homogenized with a high pressure homogenizer
Yeast
Viruses homogenized with a high pressure homogenizer
Viruses
Microalgae homogenized with a high pressure homogenizer
Microalgae
Proteins and enzymes homogenized with a high pressure homogenizer
Proteins, enzymes
Insulin homogenized with a high pressure homogenizer
Insulin

Personal Care

Face and body creams, lotions and sun care, liposomal serums, shampoos and conditioners, toothpaste, perfume emulsions and nail polish. Finer droplets give a lighter, silkier feel, better spreading and long-term stability with less emulsifier. Typical: 150–600 bar; liposomes up to 1,000 bar.

Creams homogenized with a high pressure homogenizer
Creams
Lotions homogenized with a high pressure homogenizer
Lotions
Liposomes homogenized with a high pressure homogenizer
Liposomes
Shampoo homogenized with a high pressure homogenizer
Shampoo
Toothpaste homogenized with a high pressure homogenizer
Toothpaste
Perfume homogenized with a high pressure homogenizer
Perfume
Polish homogenized with a high pressure homogenizer
Polish

Pharmaceutical

Vaccines and adjuvant emulsions, antibiotic suspensions, syrups, vitamin and mineral emulsions, parenteral lipid emulsions, liposomes, nano-suspensions and dermal creams. Droplets below 0.5 µm with a narrow distribution, aseptic execution, CIP and SIP, and documentation for GMP validation.

Vaccines homogenized with a high pressure homogenizer
Vaccines
Antibiotics homogenized with a high pressure homogenizer
Antibiotics
Syrups homogenized with a high pressure homogenizer
Syrups
Vitamins and minerals homogenized with a high pressure homogenizer
Vitamins, minerals
Lipid emulsions homogenized with a high pressure homogenizer
Lipid emulsions
Liposome suspensions homogenized with a high pressure homogenizer
Liposomes
Dermal creams homogenized with a high pressure homogenizer
Dermal creams

Typical Settings by Application: Biotech, Cosmetics and Pharma

ApplicationPressureStages and passesDesign notes
Bacterial cell disruption (E. coli)600–1,000 barSingle stage, 2–3 passesCooling between passes, closed and contained design
Yeast and algae disruption1,000–1,500 barSingle stage, 2–5 passesWear-resistant valve, heat exchanger after the valve
Cosmetic creams and lotions150–600 barTwo stage, 1 passHot process 70–80 °C, hygienic and CIP-ready
Liposomes, nano-emulsions700–1,500 bar1–5 passesNarrow size distribution, sterile filtration downstream
Parenteral lipid emulsions500–1,000 barTwo stage, several passesAseptic design, nitrogen blanketing, SIP

Frequently Asked Questions About High Pressure Homogenizers

Have a question about pressure, capacity or trials? Ask our process engineers.

A high pressure homogenizer is a plunger pump with a homogenizing valve. The pump raises a liquid to 200–1,500 bar and the valve releases it through a gap of 15–300 µm, where turbulence, cavitation and shear break fat globules, droplets, particles or cells down to a uniform size, often below one micron.

Dairy 150–250 bar, most food and cosmetic emulsions 150–600 bar, grease 150–400 bar, cell disruption and nano-emulsions 600–1,500 bar. Trials on a pilot unit confirm the setting.

Three (or five) plungers driven by a crankshaft push the product to the set pressure. The homogenizing valve holds that pressure and releases the product through a narrow gap at 100–300 m/s; almost all the pressure energy is converted into turbulence, cavitation and shear in that gap.

The first stage takes the full pressure drop and does the size reduction. A second stage adds a back-pressure of 10–20 % of the first stage, which breaks up clusters of freshly covered fat globules and keeps viscosity under control. Dairy, creams and most emulsions use two stages; some suspensions and cell disruption use a single stage.

Start from the pressure your product needs, then pick the model whose rated capacity at that pressure covers your flow with a margin. Approximate shaft power is kW = flow (m³/h) × pressure (bar) ÷ 36 ÷ 0.85; for example 10 m³/h at 200 bar needs about 65 kW.

No. A high shear mixer pre-blends and disperses at low pressure; the homogenizer then reduces droplets to below one micron. Most lines use both, the mixer first.

Yes, by about 2–2.5 °C per 100 bar (roughly 4–4.5 °F per 1,450 psi). At 1,500 bar this is more than 30 °C, so cell disruption and pharma lines cool the product directly after the valve.

Upstream of the UHT heater for most milk drinks, with a simple non-aseptic design, or downstream after UHT heating as an aseptic homogenizer for the best texture and stability of cream, coffee creamers and high-protein drinks.

Yes. Pilot homogenizers run the same valve principle as the industrial models, so trials show the right pressure, stages and passes before the machine is sized.

The pilot and laboratory models S-HM5 and C-HM1 reach up to 1,500 bar (about 21,750 psi). Bacterial cell disruption typically runs at 600–1,000 bar in 2–3 passes, yeast and algae at 1,000–1,500 bar in 2–5 passes, with cooling between passes.

Get a Quote

Find the Right Homogenizer with Protrus

Tell us your product, flow rate, inlet temperature, target droplet or particle size and where the machine will sit in your line. Protrus engineers recommend the model, pressure, valve type and materials, and can arrange trials on a pilot homogenizer before you invest.

  • Product and flow rate
  • Inlet temperature
  • Target droplet or particle size
  • Position of the homogenizer in the line

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